2025 NFL schedule preview: Ranking the 5 biggest games of the season

 

The 2025 NFL schedule is packed with exciting matchups, and we're counting down the top 10 biggest games of the season. Here are the top 5:


The fifth-biggest game of the season is the Eagles vs. Commanders matchup, which could decide which team hosts playoff games and which goes on the road as a wild card. This was last year's NFC Championship Game, where the Eagles dominated with 55 points. The Commanders will be looking for revenge after their thrilling Week 16 win over the Eagles.


At number four is the Ravens at Bills game, which could be an AFC Championship Game preview. Last year's divisional-round thriller saw the Ravens rally for a touchdown, but ultimately fall short. This matchup features two of the league's top quarterbacks, Lamar Jackson and Josh Allen, who finished first and second in last year's MVP voting.

The third-biggest game is the Chiefs at Bills matchup, which could establish the Bills as a top contender in the AFC. The Chiefs started last season 15-1, with their only loss coming at Buffalo. These two teams met again in the AFC Championship Game, where the Chiefs escaped with a 32-29 win.


At number two is the Lions at Eagles game, which could be an NFC Championship Game preview. The Eagles are ranked number one in David Helman's post-draft NFL Power Rankings, while the Lions are ranked number two. This matchup will test the Lions' ability to succeed without coordinators Ben Johnson and Aaron Glenn, who left for head coaching jobs.


The biggest game of the season is the Eagles at Chiefs matchup, a rematch of Super Bowl 59 and Super Bowl 57. This is the fifth year in a row that these two teams will face each other, a rare occurrence for teams in opposite conferences. The series is split over the past four years, with each team winning a Super Bowl and a regular-season game on the road. This matchup could set up yet another Super Bowl rematch, which would be a historic first.


These top 5 matchups promise to deliver exciting football and significant implications for the playoffs. With top quarterbacks, coaches, and teams facing off, these games will be must-watch TV for NFL fans.

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